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Help your dog move with ease and rediscover the joy of active walks with Vivaldis Grapitail 100mg Tablets, available online at PetMitra. Formulated by Vivaldis Animal Health, Grapitail features Grapiprant (100 mg)—an advanced, non-cyclooxygenase (COX) inhibiting non-steroidal anti-inflammatory drug belonging to the piprant class (EP4 receptor antagonist). Osteoarthritis is the leading cause of chronic joint pain, morning stiffness, and mobility decline in aging and large-breed dogs. Traditional NSAIDs relieve pain by broadly inhibiting COX-1 and COX-2 enzymes, which can suppress the prostaglandins necessary for gastric mucosal protection and renal blood flow. Grapitail works through a receptor-targeted mechanism: it selectively blocks the EP4 prostanoid receptor, the key gateway that mediates prostaglandin E2 (PGE2)-induced joint inflammation and pain. By sparing protective physiological pathways, Grapitail delivers targeted pain relief with an enhanced safety profile for long-term arthritis management under veterinary care